Retigabine, analytical standard

Code: 90221-25MG D2-231

Application

Retigabine may be used as a reference standard in the determination of retigabine in biological matrices using high-performance liquid chromatography coupled with...


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€124.00 25MG
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Application

Retigabine may be used as a reference standard in the determination of retigabine in biological matrices using high-performance liquid chromatography coupled with tandem mass spectrometry with positive ion atmospheric pressure chemical ionization (HPLC-APCI-MS/MS).

Biochem/physiol Actions

Retigabine (Ezogabine) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.

General description

Retigabine is an antiepileptic drug, which activatesneuronal KCNQ-type K+ channels by inducing a large hyperpolarizing shift of steady-stateactivation.

application(s)forensics and toxicologyveterinary
assay≥98.0% (HPLC)
drug controlUSDEA Schedule IV
formatneat
Gene Informationhuman ... KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479)
gradeanalytical standard
impurities≤1.0% water (calc. from elemental analysis)
InChI keyPCOBBVZJEWWZFR-UHFFFAOYSA-N
InChI1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
Quality Level100
shelf lifelimited shelf life, expiry date on the label
SMILES stringFC1=CC=C(CNC2=CC(N)=C(NC(OCC)=O)C=C2)C=C1
storage temp.2-8°C
technique(s)gas chromatography (GC): suitable, HPLC: suitable
Cas Number150812-12-7
This product has met the following criteria to qualify for the following awards:



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